2A4W

Crystal Structure Of Mitomycin C-Binding Protein Complexed with Copper(II)-Bleomycin A2

2A4W の概要

• エントリーDOI: 10.2210/pdb2a4w/pdb
• 分子名称: Mitomycin-Binding Protein, COPPER (II) ION, BLEOMYCIN A2, ... (4 entities in total)
• 機能のキーワード: alfa/beta protein, mitomycin c-binding protein, copper(ii)-bleomycin a2, structural genomics, nppsfa, national project on protein structural and functional analyses, antimicrobial protein
• 由来する生物種: Streptomyces caespitosus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32412.67

構造登録者

Danshiitsoodol, N.,de Pinho, C.A.,Matoba, Y.,Kumagai, T.,Sugiyama, M. (登録日: 2005-06-30, 公開日: 2006-07-18, 最終更新日: 2023-10-25)

• 主引用文献: Danshiitsoodol, N.,de Pinho, C.A.,Matoba, Y.,Kumagai, T.,Sugiyama, M.; The Mitomycin C (MMC)-binding Protein from MMC-producing Microorganisms Protects from the Lethal Effect of Bleomycin: Crystallographic Analysis to Elucidate the Binding Mode of the Antibiotic to the Protein; J.Mol.Biol., 360:398-408, 2006; PubMed: 16756991; DOI: 10.1016/j.jmb.2006.05.017

実験手法

X-RAY DIFFRACTION (1.5 Å)