2A4L
Human cyclin-dependent kinase 2 in complex with roscovitine
Summary for 2A4L
Entry DOI | 10.2210/pdb2a4l/pdb |
Related | 1HCK |
Descriptor | Homo sapiens cyclin-dependent kinase 2, R-ROSCOVITINE (3 entities in total) |
Functional Keywords | transferase, serine/threonine protein kinase, atp-binding, cell cycle, cell division, roscovitine, phosphorylation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 34330.94 |
Authors | De Azevedo Jr., W.F.,Kim, S.H. (deposition date: 2005-06-29, release date: 2006-10-03, Last modification date: 2024-02-14) |
Primary citation | De Azevedo, W.F.,Leclerc, S.,Meijer, L.,Havlicek, L.,Strnad, M.,Kim, S.H. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur.J.Biochem., 243:518-526, 1997 Cited by PubMed: 9030780DOI: 10.1111/j.1432-1033.1997.0518a.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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