2A3I

Structural and Biochemical Mechanisms for the Specificity of Hormone Binding and Coactivator Assembly by Mineralocorticoid Receptor

Summary for 2A3I

• Entry DOI: 10.2210/pdb2a3i/pdb
• Descriptor: Mineralocorticoid receptor, Nuclear receptor coactivator 1, residues 1430-1441, CORTICOSTERONE, ... (4 entities in total)
• Functional Keywords: transcription factor, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P08235; Nucleus : Q15788
• Total number of polymer chains: 2
• Total formula weight: 31236.22

Authors

Li, Y.,Suino, K.,Daugherty, J.,Xu, H.E. (deposition date: 2005-06-24, release date: 2005-07-19, Last modification date: 2024-02-14)

• Primary citation: Li, Y.,Suino, K.,Daugherty, J.,Xu, H.E.; Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor; Mol.Cell, 19:367-380, 2005; PubMed: 16061183; DOI: 10.1016/j.molcel.2005.06.026

Experimental method

X-RAY DIFFRACTION (1.95 Å)