2A2Q

Complex of Active-site Inhibited Human Coagulation Factor VIIa with Human Soluble Tissue Factor in the Presence of Ca2+, Mg2+, Na+, and Zn2+

2A2Q の概要

• エントリーDOI: 10.2210/pdb2a2q/pdb
• 分子名称: Coagulation factor VII, CHLORIDE ION, P-AMINO BENZAMIDINE, ... (12 entities in total)
• 機能のキーワード: factor viia, soluble tissue factor, mg2+, ca2+, na+, zn2+, hydrolase-blood clotting complex, hydrolase/blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 69947.32

構造登録者

Bajaj, S.P.,Bajaj, M.,Schmidt, A.E.,Padmanabhan, K. (登録日: 2005-06-22, 公開日: 2006-07-04, 最終更新日: 2023-11-15)

• 主引用文献: Bajaj, S.P.,Schmidt, A.E.,Agah, S.,Bajaj, M.S.,Padmanabhan, K.; High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa.; J.Biol.Chem., 281:24873-24888, 2006; PubMed: 16757484; DOI: 10.1074/jbc.M509971200

実験手法

X-RAY DIFFRACTION (1.8 Å)