2A0M

Arginase superfamily protein from Trypanosoma cruzi

2A0M の概要

• エントリーDOI: 10.2210/pdb2a0m/pdb
• 分子名称: ARGINASE SUPERFAMILY PROTEIN, CHLORIDE ION (3 entities in total)
• 機能のキーワード: structural genomics, arginase, psi, protein structure initiative, structural genomics of pathogenic protozoa consortium, sgpp, hydrolase
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34713.73

構造登録者

Arakaki, T.L.,Merritt, E.A.,Structural Genomics of Pathogenic Protozoa Consortium (SGPP) (登録日: 2005-06-16, 公開日: 2005-07-05, 最終更新日: 2024-04-03)

主引用文献

Fan, E.,Baker, D.,Fields, S.,Gelb, M.H.,Buckner, F.S.,Van Voorhis, W.C.,Phizicky, E.,Dumont, M.,Mehlin, C.,Grayhack, E.,Sullivan, M.,Verlinde, C.,Detitta, G.,Meldrum, D.R.,Merritt, E.A.,Earnest, T.,Soltis, M.,Zucker, F.,Myler, P.J.,Schoenfeld, L.,Kim, D.,Worthey, L.,Lacount, D.,Vignali, M.,Li, J.,Mondal, S.,Massey, A.,Carroll, B.,Gulde, S.,Luft, J.,Desoto, L.,Holl, M.,Caruthers, J.,Bosch, J.,Robien, M.,Arakaki, T.,Holmes, M.,Le Trong, I.,Hol, W.G.
Structural genomics of pathogenic protozoa: an overview.
Methods Mol.Biol., 426:497-513, 2008

PubMed Abstract: The Structural Genomics of Pathogenic Protozoa (SGPP) Consortium aimed to determine crystal structures of proteins from trypanosomatid and malaria parasites in a high throughput manner. The pipeline of target selection, protein production, crystallization, and structure determination, is sketched. Special emphasis is given to a number of technology developments including domain prediction, the use of "co-crystallants," and capillary crystallization. "Fragment cocktail crystallography" for medical structural genomics is also described.

PubMed: 18542886
DOI: 10.1007/978-1-60327-058-8_33

実験手法

X-RAY DIFFRACTION (1.603 Å)