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2ZMC

Crystal structure of human mitotic checkpoint kinase Mps1 catalytic domain apo form

Summary for 2ZMC
Entry DOI10.2210/pdb2zmc/pdb
Related2ZMD
DescriptorDual specificity protein kinase TTK, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL (3 entities in total)
Functional Keywordskinase, mps1, mitosis, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight44658.78
Authors
Chu, M.L.H.,Chavas, L.M.G.,Douglas, K.T.,Eyers, P.A.,Tabernero, L. (deposition date: 2008-04-16, release date: 2008-05-13, Last modification date: 2023-11-01)
Primary citationChu, M.L.,Chavas, L.M.,Douglas, K.T.,Eyers, P.A.,Tabernero, L.
Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125.
J.Biol.Chem., 283:21495-21500, 2008
Cited by
PubMed: 18480048
DOI: 10.1074/jbc.M803026200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.14 Å)
Structure validation

217157

数据于2024-03-13公开中

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