2ZCK
Crystal structure of a ternary complex between PSA, a substrat-acyl intermediate and an activating antibody
Summary for 2ZCK
Entry DOI | 10.2210/pdb2zck/pdb |
Related | 2ZCH 2ZCL |
Descriptor | Prostate-specific antigen, KGISSQY, monoclonal antibody 8G8F5 Fab, ... (6 entities in total) |
Functional Keywords | human psa, antibodies, kallikrein related peptidases, prostate cancer, glycoprotein, hydrolase, protease, secreted, serine protease, zymogen, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P07288 |
Total number of polymer chains | 4 |
Total formula weight | 75558.69 |
Authors | Menez, R.,Stura, E.,Jolivet-Reynaud, C. (deposition date: 2007-11-09, release date: 2008-01-29, Last modification date: 2023-11-01) |
Primary citation | Michel, S.,Muller, B.H.,Bossus, M.,Ducancel, F.,Jolivet-Reynaud, C.,Stura, E.A. Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody J.Mol.Biol., 376:1021-1033, 2008 Cited by PubMed: 18187150DOI: 10.1016/j.jmb.2007.11.052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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