2Z94
Complex structure of SARS-CoV 3C-like protease with TDT
Summary for 2Z94
Entry DOI | 10.2210/pdb2z94/pdb |
Descriptor | Replicase polyprotein 1ab, ZINC ION, 4-methylbenzene-1,2-dithiol, ... (4 entities in total) |
Functional Keywords | complex, hydrolase |
Biological source | SARS coronavirus |
Cellular location | Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity). Helicase: Host endoplasmic reticulum-Golgi intermediate compartment (Potential). Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region (By similarity): P59641 |
Total number of polymer chains | 1 |
Total formula weight | 34098.31 |
Authors | Lee, C.C.,Wang, A.H. (deposition date: 2007-09-17, release date: 2007-12-25, Last modification date: 2023-11-01) |
Primary citation | Lee, C.C.,Kuo, C.J.,Hsu, M.F.,Liang, P.H.,Fang, J.M.,Shie, J.J.,Wang, A.H. Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors Febs Lett., 581:5454-5458, 2007 Cited by PubMed: 17981158DOI: 10.1016/j.febslet.2007.10.048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
Download full validation report