2YPV

Crystal structure of the Meningococcal vaccine antigen factor H binding protein in complex with a bactericidal antibody

Summary for 2YPV

Entry DOI	10.2210/pdb2ypv/pdb
Descriptor	LIPOPROTEIN, FAB 12C1, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	immune system, vaccine, monoclonal antibody, mab, epitope mapping
Biological source	NEISSERIA MENINGITIDIS MC58 More
Total number of polymer chains	3
Total formula weight	74636.98
Authors	Malito, E.,Veggi, D.,Bottomley, M.J. (deposition date: 2012-11-01, release date: 2013-02-20, Last modification date: 2023-12-20)
Primary citation	Malito, E.,Faleri, A.,Lo Surdo, P.,Veggi, D.,Maruggi, G.,Grassi, E.,Cartocci, E.,Bertoldi, I.,Genovese, A.,Santini, L.,Romagnoli, G.,Borgogni, E.,Brier, S.,Lo Passo, C.,Domina, M.,Castellino, F.,Felici, F.,Van Der Veen, S.,Johnson, S.,Lea, S.M.,Tang, C.M.,Pizza, M.,Savino, S.,Norais, N.,Rappuoli, R.,Bottomley, M.J.,Masignani, V. Defining a Protective Epitope on Factor H Binding Protein, a Key Meningococcal Virulence Factor and Vaccine Antigen. Proc.Natl.Acad.Sci.USA, 110:3304-, 2013 Cited by PubMed: 23396847 DOI: 10.1073/PNAS.1222845110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation