2XUC

Natural product-guided discovery of a fungal chitinase inhibitor

Summary for 2XUC

• Entry DOI: 10.2210/pdb2xuc/pdb
• Related: 2XVN 2XVP
• Descriptor: CHITINASE, 1-methyl-3-(N-methylcarbamimidoyl)urea, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase, aspergillosis
• Biological source: ASPERGILLUS FUMIGATUS
• Total number of polymer chains: 3
• Total formula weight: 103362.25

Authors

Rush, C.L.,Schuttelkopf, A.W.,Hurtado-Guerrero, R.,Blair, D.E.,Ibrahim, A.F.M.,Desvergnes, S.,Eggleston, I.M.,van Aalten, D.M.F. (deposition date: 2010-10-18, release date: 2010-10-27, Last modification date: 2019-01-23)

• Primary citation: Rush, C.L.,Schuttelkopf, A.W.,Hurtado-Guerrero, R.,Blair, D.E.,Ibrahim, A.F.M.,Desvergnes, S.,Eggleston, I.M.,van Aalten, D.M.F.; Natural Product-Guided Discovery of a Fungal Chitinase Inhibitor.; Chem.Biol., 17:1275-, 2010; PubMed: 21168763; DOI: 10.1016/J.CHEMBIOL.2010.07.018

Experimental method

X-RAY DIFFRACTION (2.3 Å)