2XOW
Structure of GlpG in complex with a mechanism-based isocoumarin inhibitor
Summary for 2XOW
Entry DOI | 10.2210/pdb2xow/pdb |
Related | 2IC8 2IRV 2XOV |
Descriptor | RHOMBOID PROTEASE GLPG, 5-AMINO-2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID, nonyl beta-D-glucopyranoside, ... (4 entities in total) |
Functional Keywords | hydrolase, membrane protein, intramembrane protease |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 1 |
Total formula weight | 25325.54 |
Authors | Vinothkumar, K.R.,Strisovsky, K.,Andreeva, A.,Christova, Y.,Verhelst, S.,Freeman, M. (deposition date: 2010-08-24, release date: 2010-10-13, Last modification date: 2023-12-20) |
Primary citation | Vinothkumar, K.R.,Strisovsky, K.,Andreeva, A.,Christova, Y.,Verhelst, S.,Freeman, M. The Structural Basis for Catalysis and Substrate Specificity of a Rhomboid Protease Embo J., 29:3797-, 2010 Cited by PubMed: 20890268DOI: 10.1038/EMBOJ.2010.243 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.09 Å) |
Structure validation
Download full validation report