2W4K

X-ray structure of a DAP-Kinase 2-302

Summary for 2W4K

Entry DOI	10.2210/pdb2w4k/pdb
Related	1IG1 1JKK 1JKL 1JKS 1JKT 1P4F 2JL2 2W4J 2XUU 4B4L
Descriptor	DEATH-ASSOCIATED PROTEIN KINASE 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	polymorphism, phosphoprotein, calmodulin-binding, serine/threonine-protein kinase, nucleotide-binding, alternative splicing, dapk, kinase, complex, apoptosis, cytoplasm, ank repeat, calmodulin, transferase, atp-binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: P53355
Total number of polymer chains	1
Total formula weight	35147.16
Authors	De Diego, I.,Kuper, J.,Lehmann, F.,Wilmanns, M. (deposition date: 2008-11-27, release date: 2009-12-22, Last modification date: 2023-12-13)
Primary citation	Temmerman, K.,De Diego, I.,Pogenberg, V.,Simon, B.,Jonko, W.,Li, X.,Wilmanns, M. A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity. Chem.Biol., 21:264-, 2014 Cited by PubMed: 24440081 DOI: 10.1016/J.CHEMBIOL.2013.12.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation