2V7D

14-3-3 protein zeta in complex with Thr758 phosphorylated integrin beta2 peptide

Summary for 2V7D

• Entry DOI: 10.2210/pdb2v7d/pdb
• Related: 1A37 1A38 1A4O
• Descriptor: 14-3-3 PROTEIN ZETA/DELTA, INTEGRIN BETA CHAIN, BETA 2 VARIANT (3 entities in total)
• Functional Keywords: membrane, integrin, receptor, cytoplasm, acetylation, transmembrane, beta2 integrin, phosphorylation, disease mutation, pyrrolidone carboxylic acid, 14-3-3 zeta, glycoprotein, cell adhesion, signaling protein
• Biological source: BOS TAURUS (BOVINE); More
• Cellular location: Cytoplasm: P63103
• Total number of polymer chains: 8
• Total formula weight: 116205.63

Authors

Takala, H.,Ylanne, J. (deposition date: 2007-07-30, release date: 2008-06-24, Last modification date: 2023-12-13)

• Primary citation: Takala, H.,Nurminen, E.,Nurmi, S.M.,Aatonen, M.,Strandin, T.,Takatalo, M.,Kiema, T.,Gahmberg, C.G.,Ylanne, J.,Fagerholm, S.C.; Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.; Blood, 112:1853-, 2008; PubMed: 18550856; DOI: 10.1182/BLOOD-2007-12-127795

Experimental method

X-RAY DIFFRACTION (2.5 Å)