2TMN
CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
Summary for 2TMN
Entry DOI | 10.2210/pdb2tmn/pdb |
Descriptor | Thermolysin, CALCIUM ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, metalloproteinase, hydrolase/hydrolase inhibitor |
Biological source | Bacillus thermoproteolyticus |
Cellular location | Secreted: P00800 |
Total number of polymer chains | 1 |
Total formula weight | 34798.19 |
Authors | Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. (deposition date: 1987-06-29, release date: 1989-01-09, Last modification date: 2024-05-22) |
Primary citation | Tronrud, D.E.,Monzingo, A.F.,Matthews, B.W. Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin. Eur.J.Biochem., 157:261-268, 1986 Cited by PubMed: 3709536DOI: 10.1111/j.1432-1033.1986.tb09664.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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