2SRT

CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 AT PH 5.5 AND 40OC COMPLEXED WITH INHIBITOR

Replaces:  1SRT

Summary for 2SRT

• Entry DOI: 10.2210/pdb2srt/pdb
• Descriptor: STROMELYSIN-1, ZINC ION, N-(R-CARBOXY-ETHYL)-ALPHA-(S)-(2-PHENYLETHYL)GLYCYL-L-ARGININE-N-PHENYLAMIDE (3 entities in total)
• Functional Keywords: metzincin, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix (Probable): P08254
• Total number of polymer chains: 1
• Total formula weight: 20030.93

Authors

Gooley, P.R.,O'Connell, J.F. (deposition date: 1995-03-22, release date: 1995-07-10, Last modification date: 2021-09-29)

• Primary citation: Gooley, P.R.,O'Connell, J.F.,Marcy, A.I.,Cuca, G.C.,Salowe, S.P.,Bush, B.L.,Hermes, J.D.,Esser, C.K.,Hagmann, W.K.,Springer, J.P.,Johnson, B.A.; The NMR structure of the inhibited catalytic domain of human stromelysin-1.; Nat.Struct.Biol., 1:111-118, 1994; PubMed: 7656014; DOI: 10.1038/nsb0294-111

Experimental method

SOLUTION NMR