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2SGP

PRO 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5

Summary for 2SGP
Entry DOI10.2210/pdb2sgp/pdb
DescriptorPROTEINASE B, OVOMUCOID INHIBITOR, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordscomplex (serine protease-inhibitor), serine proteinase, protein inhibitor, hydrolase-inhibitor complex, hydrolase/inhibitor
Biological sourceMeleagris gallopavo (turkey)
More
Cellular locationSecreted: P68390
Total number of polymer chains2
Total formula weight24317.45
Authors
Huang, K.,Lu, W.,Anderson, S.,Laskowski Jr., M.,James, M.N.G. (deposition date: 1999-03-25, release date: 2001-01-31, Last modification date: 2023-08-30)
Primary citationBateman, K.S.,Huang, K.,Anderson, S.,Lu, W.,Qasim, M.A.,Laskowski Jr., M.,James, M.N.
Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305:839-849, 2001
Cited by
PubMed: 11162096
DOI: 10.1006/jmbi.2000.4343
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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