2RUD

Solution structure of the peptidyl prolyl cis-trans isomerase domain of C113D mutant human Pin1 with sulfate ion

Summary for 2RUD

• Entry DOI: 10.2210/pdb2rud/pdb
• Related: 2RUC
• NMR Information: BMRB: 11560
• Descriptor: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (1 entity in total)
• Functional Keywords: protein/cis-trans-isomerase, ppiase, isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q13526
• Total number of polymer chains: 1
• Total formula weight: 13133.68

Authors

Xu, N.,Tamari, Y.,Tochio, N.,Tate, S. (deposition date: 2014-03-25, release date: 2014-12-17, Last modification date: 2023-06-14)

• Primary citation: Xu, N.,Tochio, N.,Wang, J.,Tamari, Y.,Uewaki, J.,Utsunomiya-Tate, N.,Igarashi, K.,Shiraki, T.,Kobayashi, N.,Tate, S.; The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.; Biochemistry, 53:5568-5578, 2014; PubMed: 25100325; DOI: 10.1021/bi5007817

Experimental method

SOLUTION NMR