2RT5

Structural insights into the recruitment of SMRT by the co-repressor SHARP under phosphorylative regulation

Summary for 2RT5

• Entry DOI: 10.2210/pdb2rt5/pdb
• NMR Information: BMRB: 11504
• Descriptor: Msx2-interacting protein, peptide from Silencing mediator of retinoic acid and thyroid hormone receptor (2 entities in total)
• Functional Keywords: sharp, spoc domain, smrt, phosphorylation, transcription regulator
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q96T58 Q9Y618
• Total number of polymer chains: 2
• Total formula weight: 19574.28

Authors

Mikami, S.,Kanaba, T.,Mishima, M. (deposition date: 2013-04-22, release date: 2013-12-04, Last modification date: 2022-08-24)

• Primary citation: Mikami, S.,Kanaba, T.,Takizawa, N.,Kobayashi, A.,Maesaki, R.,Fujiwara, T.,Ito, Y.,Mishima, M.; Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.; Structure, 22:35-46, 2014; PubMed: 24268649; DOI: 10.1016/j.str.2013.10.007

Experimental method

SOLUTION NMR