2RPN

A crucial role for high intrinsic specificity in the function of yeast SH3 domains

Summary for 2RPN

Entry DOI	10.2210/pdb2rpn/pdb
Descriptor	Actin-binding protein, Actin-regulating kinase 1 (2 entities in total)
Functional Keywords	sh3 domain, extended peptide, 3-10 helix, acetylation, actin-binding, cytoplasm, cytoskeleton, phosphoprotein, structural protein
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Cytoplasm, cytoskeleton, actin patch: P15891 P53974
Total number of polymer chains	2
Total formula weight	8721.61
Authors	Stollar, E.J.,Garcia, B.,Chong, A.,Forman-Kay, J.,Davidson, A. (deposition date: 2008-06-12, release date: 2009-06-16, Last modification date: 2022-03-16)
Primary citation	Stollar, E.J.,Garcia, B.,Chong, P.A.,Rath, A.,Lin, H.,Forman-Kay, J.D.,Davidson, A.R. Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284:26918-26927, 2009 Cited by PubMed: 19590096 DOI: 10.1074/jbc.M109.028431 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation