2RNX
The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP
Summary for 2RNX
Entry DOI | 10.2210/pdb2rnx/pdb |
Related | 2RNW |
Descriptor | Histone acetyltransferase PCAF, Histone H3 (2 entities in total) |
Functional Keywords | bromodomain, histone, acetyltransferase, acyltransferase, cell cycle, host-virus interaction, nucleus, polymorphism, transcription, transcription regulation, acetylation, chromosomal protein, dna damage, dna repair, dna-binding, methylation, nucleosome core, phosphoprotein, transferase-nuclear protein complex, transferase/nuclear protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (By similarity): Q92831 Nucleus: P61830 |
Total number of polymer chains | 2 |
Total formula weight | 15559.00 |
Authors | Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Zhou, M.M. (deposition date: 2008-02-03, release date: 2008-05-06, Last modification date: 2023-11-15) |
Primary citation | Zeng, L.,Zhang, Q.,Gerona-Navarro, G.,Moshkina, N.,Zhou, M.M. Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300 Structure, 16:643-652, 2008 Cited by PubMed: 18400184DOI: 10.1016/j.str.2008.01.010 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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