2RNM

Structure of The HET-s(218-289) prion in its amyloid form obtained by solid-state NMR

Summary for 2RNM

Entry DOI	10.2210/pdb2rnm/pdb
Descriptor	Small s protein (1 entity in total)
Functional Keywords	het-s(218-289), beta-solenoid, prion, amyloid fibril, parallel beta-sheets, hydrophobic core, salt bridges, asparagine ladders, beta-helix, protein fibril
Biological source	Podospora anserina (Fungi)
Cellular location	Cytoplasm: Q03689
Total number of polymer chains	5
Total formula weight	43338.25
Authors	Wasmer, C.,Lange, A.,Van Melckebeke, H.,Siemer, A.,Riek, R.,Meier, B.H. (deposition date: 2008-01-24, release date: 2008-04-01, Last modification date: 2015-07-08)
Primary citation	Wasmer, C.,Lange, A.,Van Melckebeke, H.,Siemer, A.B.,Riek, R.,Meier, B.H. Amyloid fibrils of the HET-s(218-289) prion form a beta solenoid with a triangular hydrophobic core Science, 319:1523-1526, 2008 Cited by PubMed: 18339938 DOI: 10.1126/science.1151839 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation