2RCZ

Structure of the second PDZ domain of ZO-1

Summary for 2RCZ

Entry DOI	10.2210/pdb2rcz/pdb
Descriptor	Tight junction protein ZO-1 (2 entities in total)
Functional Keywords	pdz, domain-swapping, cell junction, membrane, phosphorylation, sh3 domain, tight junction, protein binding
Biological source	Homo sapiens (human)
Cellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
Total number of polymer chains	2
Total formula weight	18006.61
Authors	Lavie, A.,Lye, M.F. (deposition date: 2007-09-20, release date: 2007-10-09, Last modification date: 2024-02-21)
Primary citation	Fanning, A.S.,Lye, M.F.,Anderson, J.M.,Lavie, A. Domain swapping within PDZ2 is responsible for dimerization of ZO proteins. J.Biol.Chem., 282:37710-37716, 2007 Cited by PubMed: 17928286 DOI: 10.1074/jbc.M707255200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation