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2R2O

Crystal structure of the effector domain of human Plexin B1

Summary for 2R2O
Entry DOI10.2210/pdb2r2o/pdb
DescriptorPlexin-B1, UNKNOWN ATOM OR ION (3 entities in total)
Functional Keywordsplexin, effector domain, structural genomics, structural genomics consortium, sgc, glycoprotein, membrane, phosphorylation, receptor, secreted, transmembrane, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted. Isoform 3: Secreted: O43157
Total number of polymer chains2
Total formula weight31068.52
Authors
Tong, Y.,Tempel, W.,Shen, L.,Arrowsmith, C.H.,Edwards, A.M.,Sundstrom, M.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2007-08-27, release date: 2007-09-04, Last modification date: 2017-10-25)
Primary citationTong, Y.,Chugha, P.,Hota, P.K.,Alviani, R.S.,Li, M.,Tempel, W.,Shen, L.,Park, H.W.,Buck, M.
Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain.
J.Biol.Chem., 282:37215-37224, 2007
Cited by
PubMed: 17916560
DOI: 10.1074/jbc.M703800200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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