2PYK

Crystal structure of Staphylococcal nuclease variant V66Q/P117G/H124L/S128A at room temperature

Summary for 2PYK

Entry DOI	10.2210/pdb2pyk/pdb
Related	1U9R 2PW5 2PW7
Descriptor	Thermonuclease (2 entities in total)
Functional Keywords	staphylococcal nuclease, nuclease, hyperstable variant, internal waters, hydrolase
Biological source	Staphylococcus aureus
Cellular location	Secreted (By similarity): Q8NXI6
Total number of polymer chains	1
Total formula weight	16791.28
Authors	Schlessman, J.L.,Abe, C.,Garcia-Moreno, E.B. (deposition date: 2007-05-16, release date: 2008-05-20, Last modification date: 2024-04-03)
Primary citation	Schlessman, J.L.,Abe, C.,Gittis, A.,Karp, D.A.,Dolan, M.A.,Garcia-Moreno, E.B. Crystallographic study of hydration of an internal cavity in engineered proteins with buried polar or ionizable groups. Biophys.J., 94:3208-3216, 2008 Cited by PubMed: 18178652 DOI: 10.1529/biophysj.107.122473 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation