2PSY
Crystal Structure of Human Kallikrein 5 in complex with Leupeptin and Zinc
Summary for 2PSY
Entry DOI | 10.2210/pdb2psy/pdb |
Related PRD ID | PRD_000216 |
Descriptor | Kallikrein-5, LEUPEPTIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | zinc inhibition, stratum corneum, glcosylation, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q9Y337 |
Total number of polymer chains | 2 |
Total formula weight | 26243.13 |
Authors | Debela, M.,Bode, W.,Goettig, P. (deposition date: 2007-05-07, release date: 2007-09-11, Last modification date: 2023-08-30) |
Primary citation | Debela, M.,Goettig, P.,Magdolen, V.,Huber, R.,Schechter, N.M.,Bode, W. Structural basis of the zinc inhibition of human tissue kallikrein 5. J.Mol.Biol., 373:1017-1031, 2007 Cited by PubMed: 17881000DOI: 10.1016/j.jmb.2007.08.042 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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