2PS8
Y295F Trichodiene Synthase: Complex With Mg and Pyrophosphate
Summary for 2PS8
Entry DOI | 10.2210/pdb2ps8/pdb |
Related | 1JFA 1JFG 1KIZ 1YYQ 2PS7 |
Descriptor | Trichodiene synthase, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | terpenoid synthase fold, site-directed mutagenesis, magnesium, pyrophosphate, ethylene glycol, lyase |
Biological source | Fusarium sporotrichioides |
Total number of polymer chains | 2 |
Total formula weight | 88442.21 |
Authors | Vedula, L.S.,Cane, D.E.,Christianson, D.W. (deposition date: 2007-05-04, release date: 2007-12-18, Last modification date: 2023-08-30) |
Primary citation | Vedula, L.S.,Jiang, J.,Zakharian, T.,Cane, D.E.,Christianson, D.W. Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469:184-194, 2008 Cited by PubMed: 17996718DOI: 10.1016/j.abb.2007.10.015 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.67 Å) |
Structure validation
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