2P42

Complex of a camelid single-domain vhh antibody fragment with RNASE A at 1.8A resolution: SE3-mono-2 crystal form with three se-met sites (M34, M51, M83) in vhh scaffold

Summary for 2P42

Entry DOI	10.2210/pdb2p42/pdb
Descriptor	Ribonuclease pancreatic, ANTIBODY CAB-RN05, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	semet phasing, camelid single-domain antibody, vhh, cab-rn05, rnase a, yeast surface display., hydrolase-immune system complex, hydrolase/immune system
Biological source	Camelus dromedarius (Arabian camel) More
Cellular location	Secreted: P61823
Total number of polymer chains	4
Total formula weight	53931.26
Authors	Tereshko, V.,Uysal, S.,Koide, A.,Margalef, K.,Koide, S.,Kossiakoff, A.A. (deposition date: 2007-03-11, release date: 2008-03-11, Last modification date: 2011-07-13)
Primary citation	Tereshko, V.,Uysal, S.,Koide, A.,Margalef, K.,Koide, S.,Kossiakoff, A.A. Toward chaperone-assisted crystallography: protein engineering enhancement of crystal packing and X-ray phasing capabilities of a camelid single-domain antibody (VHH) scaffold Protein Sci., 17:1175-1187, 2008 Cited by PubMed: 18445622 DOI: 10.1110/ps.034892.108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation