2OT5
Crystal structure of the HIV gp41 core with the enfuvirtide resistance mutation N43D
Summary for 2OT5
| Entry DOI | 10.2210/pdb2ot5/pdb |
| Descriptor | HIV-1 gp41 glycoprotein (2 entities in total) |
| Functional Keywords | gp41, coiled-coil, viral protein |
| Biological source | human immunodeficiency virus type 1 (Virus) |
| Total number of polymer chains | 1 |
| Total formula weight | 7880.74 |
| Authors | Bai, X.,Seedorff, J.E.,Green, J.,Dwyer, J.J. (deposition date: 2007-02-07, release date: 2008-06-17, Last modification date: 2023-08-30) |
| Primary citation | Bai, X.,Wilson, K.L.,Seedorff, J.E.,Ahrens, D.,Green, J.,Davison, D.K.,Jin, L.,Stanfield-Oakley, S.A.,Mosier, S.M.,Melby, T.E.,Cammack, N.,Wang, Z.,Greenberg, M.L.,Dwyer, J.J. Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. Biochemistry, 47:6662-6670, 2008 Cited by PubMed: 18507398DOI: 10.1021/bi702509d PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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