2OC2

Structure of testis ACE with RXPA380

Summary for 2OC2

• Entry DOI: 10.2210/pdb2oc2/pdb
• Descriptor: Angiotensin-converting enzyme, somatic isoform, ZINC ION, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: enzyme-inhibitor complex, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Angiotensin-converting enzyme, soluble form: Secreted. Cell membrane; Single-pass type I membrane protein: P12821
• Total number of polymer chains: 1
• Total formula weight: 69051.14

Authors

Corradi, H.R.,Anthony, C.S.,Schwager, S.L.,Redelinghuys, P.,Georgiadis, D.,Dive, V.,Acharya, K.R.,Sturrock, E.D. (deposition date: 2006-12-20, release date: 2007-05-22, Last modification date: 2024-04-03)

• Primary citation: Corradi, H.R.,Chitapi, I.,Sewell, B.T.,Georgiadis, D.,Dive, V.,Sturrock, E.D.,Acharya, K.R.; The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380.; Biochemistry, 46:5473-5478, 2007; PubMed: 17439247; DOI: 10.1021/bi700275e

Experimental method

X-RAY DIFFRACTION (2.25 Å)