2NWG
Structure of CXCL12:heparin disaccharide complex
Summary for 2NWG
| Entry DOI | 10.2210/pdb2nwg/pdb |
| Related PRD ID | PRD_900026 |
| Descriptor | Stromal cell-derived factor 1, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total) |
| Functional Keywords | protein-glycosaminoglycan complex, cytokine, signaling protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 17143.95 |
| Authors | Murphy, J.W.,Cho, Y.,Lolis, E. (deposition date: 2006-11-14, release date: 2007-02-13, Last modification date: 2023-12-27) |
| Primary citation | Murphy, J.W.,Cho, Y.,Sachpatzidis, A.,Fan, C.,Hodsdon, M.E.,Lolis, E. Structural and Functional Basis of CXCL12 (Stromal Cell-derived Factor-1{alpha}) Binding to Heparin J.Biol.Chem., 282:10018-10027, 2007 Cited by PubMed: 17264079DOI: 10.1074/jbc.M608796200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
Download full validation report
