2NNO

Structure of inhibitor binding to Carbonic Anhydrase II

Summary for 2NNO

Entry DOI	10.2210/pdb2nno/pdb
Related	2NMX 2NN1 2NN7 2NNG 2NNS 2NNV
Descriptor	Carbonic anhydrase 2, ZINC ION, 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, ... (5 entities in total)
Functional Keywords	zinc metalloenzyme, sulfonamide, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	30119.69
Authors	Christianson, D.W.,Jude, K.M. (deposition date: 2006-10-24, release date: 2007-05-08, Last modification date: 2023-08-30)
Primary citation	Srivastava, D.K.,Jude, K.M.,Banerjee, A.L.,Haldar, M.,Manokaran, S.,Kooren, J.,Mallik, S.,Christianson, D.W. Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II. J.Am.Chem.Soc., 129:5528-5537, 2007 Cited by PubMed: 17407288 DOI: 10.1021/ja068359w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.01 Å)

Structure validation