2MXU

42-Residue Beta Amyloid Fibril

Summary for 2MXU

Entry DOI	10.2210/pdb2mxu/pdb
NMR Information	BMRB: 25429
Descriptor	Amyloid beta A4 protein (1 entity in total)
Functional Keywords	amyloid fibril, amyloid beta, protein fibril
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: P05067
Total number of polymer chains	12
Total formula weight	54241.04
Authors	Xiao, Y.,Ma, B.,McElheny, D.,Parthasarathy, S.,Long, F.,Hoshi, M.,Nussinov, R.,Ishii, Y. (deposition date: 2015-01-14, release date: 2015-05-06, Last modification date: 2015-06-17)
Primary citation	Xiao, Y.,Ma, B.,McElheny, D.,Parthasarathy, S.,Long, F.,Hoshi, M.,Nussinov, R.,Ishii, Y. A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22:499-505, 2015 Cited by PubMed: 25938662 DOI: 10.1038/nsmb.2991 PDB entries with the same primary citation
Experimental method	SOLID-STATE NMR

Structure validation