2MWP
Solution structure of 53BP1 tandem Tudor domains in complex with a p53K382me2 peptide
Summary for 2MWP
Entry DOI | 10.2210/pdb2mwp/pdb |
Related | 2MWO |
NMR Information | BMRB: 25348 |
Descriptor | Tumor suppressor p53-binding protein 1, Cellular tumor antigen p53 (2 entities in total) |
Functional Keywords | cell cycle, dna damage response, transcription-antitumor protein complex, transcription/antitumor protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q12888 Cytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637 |
Total number of polymer chains | 2 |
Total formula weight | 15440.61 |
Authors | Cui, G.,Botuyan, M.V.,Mer, G. (deposition date: 2014-11-15, release date: 2014-12-10, Last modification date: 2015-03-18) |
Primary citation | Tong, Q.,Cui, G.,Botuyan, M.V.,Rothbart, S.B.,Hayashi, R.,Musselman, C.A.,Singh, N.,Appella, E.,Strahl, B.D.,Mer, G.,Kutateladze, T.G. Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1. Structure, 23:312-321, 2015 Cited by PubMed: 25579814DOI: 10.1016/j.str.2014.11.013 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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