2MM3

Solution NMR structure of the ternary complex of human ileal bile acid-binding protein with glycocholate and glycochenodeoxycholate

Summary for 2MM3

Entry DOI	10.2210/pdb2mm3/pdb
NMR Information	BMRB: 19843
Descriptor	Gastrotropin, GLYCOCHOLIC ACID, GLYCOCHENODEOXYCHOLIC ACID (3 entities in total)
Functional Keywords	lipid-binding protein, orthogonal beta sheets, positive binding cooperativity, site-selectivity, enterohepatic circulation, lipid binding protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	15173.28
Authors	Horvath, G.,Egyed, O.,Bencsura, A.,Simon, A.,Tochtrop, G.P.,DeKoster, G.T.,Covey, D.F.,Cistola, D.P.,Toke, O. (deposition date: 2014-03-07, release date: 2014-05-07, Last modification date: 2023-06-14)
Primary citation	Horvath, G.,Bencsura, A.,Simon, A.,Tochtrop, G.P.,DeKoster, G.T.,Covey, D.F.,Cistola, D.P.,Toke, O. Structural determinants of ligand binding in the ternary complex of human ileal bile acid binding protein with glycocholate and glycochenodeoxycholate obtained from solution NMR FEBS J., 283:541-555, 2016 Cited by PubMed: 26613247 DOI: 10.1111/febs.13610 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation