2MLR
Membrane Bilayer complex with Matrix Metalloproteinase-12 at its Alpha-face
Summary for 2MLR
Entry DOI | 10.2210/pdb2mlr/pdb |
Related | 2MLS 2POJ |
Descriptor | Macrophage metalloelastase, ZINC ION, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | membrane-binding of soluble metalloproteinase mmp-12, catalytic domain, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix : P39900 |
Total number of polymer chains | 1 |
Total formula weight | 103295.93 |
Authors | Koppisetti, R.K.,Fulcher, Y.G.,Prior, S.H.,Lenoir, M.,Overduin, M.,Van Doren, S.R. (deposition date: 2014-03-04, release date: 2014-12-03, Last modification date: 2024-05-01) |
Primary citation | Koppisetti, R.K.,Fulcher, Y.G.,Jurkevich, A.,Prior, S.H.,Xu, J.,Lenoir, M.,Overduin, M.,Van Doren, S.R. Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12. Nat Commun, 5:5552-5552, 2014 Cited by PubMed: 25412686DOI: 10.1038/ncomms6552 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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