2MHS

NMR Structure of human Mcl-1

Summary for 2MHS

• Entry DOI: 10.2210/pdb2mhs/pdb
• NMR Information: BMRB: 19654
• Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1 (1 entity in total)
• Functional Keywords: mcl-1, bcl-2 family, bh domain, apoptosis, cancer drug, gft nmr
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass membrane protein (Potential): Q07820
• Total number of polymer chains: 1
• Total formula weight: 18866.35

Authors

Liu, G.,Poppe, L.,Aoki, K.,Yamane, H.,Lewis, J.,Szyperski, T. (deposition date: 2013-12-04, release date: 2014-05-14, Last modification date: 2023-06-14)

• Primary citation: Liu, G.,Poppe, L.,Aoki, K.,Yamane, H.,Lewis, J.,Szyperski, T.; High-Quality NMR Structure of Human Anti-Apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design.; Plos One, 9:e96521-e96521, 2014; PubMed: 24789074; DOI: 10.1371/journal.pone.0096521

Experimental method

SOLUTION NMR