2MGZ

Solution structure of RBFOX family ASD-1 RRM and SUP-12 RRM in ternary complex with RNA

Summary for 2MGZ

• Entry DOI: 10.2210/pdb2mgz/pdb
• Related: 2RU3
• NMR Information: BMRB: 19609
• Descriptor: Protein ASD-1, isoform a, Protein SUP-12, isoform a, RNA (5'-R(*UP*GP*CP*AP*UP*GP*GP*UP*GP*UP*GP*C)-3') (3 entities in total)
• Functional Keywords: solution structure, protein-rna complex, ternary complex, rrm (rna recognition motif), rna binding protein-rna complex, rna binding protein/rna
• Biological source: Caenorhabditis elegans (nematode); More
• Total number of polymer chains: 3
• Total formula weight: 26044.34

Authors

Takahashi, M.,Kuwasako, K.,Unzai, S.,Tsuda, K.,Yoshikawa, S.,He, F.,Kobayashi, N.,Guntert, P.,Shirouzu, M.,Ito, T.,Tanaka, A.,Yokoyama, S.,Hagiwara, M.,Kuroyanagi, H.,Muto, Y. (deposition date: 2013-11-12, release date: 2014-08-13, Last modification date: 2015-03-18)

• Primary citation: Kuwasako, K.,Takahashi, M.,Unzai, S.,Tsuda, K.,Yoshikawa, S.,He, F.,Kobayashi, N.,Guntert, P.,Shirouzu, M.,Ito, T.,Tanaka, A.,Yokoyama, S.,Hagiwara, M.,Kuroyanagi, H.,Muto, Y.; RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing; Nat.Struct.Mol.Biol., 21:778-786, 2014; PubMed: 25132178; DOI: 10.1038/nsmb.2870

Experimental method

SOLUTION NMR