2MET
NMR spatial structure of the trimeric mutant TM domain of VEGFR2 receptor.
Summary for 2MET
Entry DOI | 10.2210/pdb2met/pdb |
Related | 2MEU |
NMR Information | BMRB: 19531 |
Descriptor | Vascular endothelial growth factor receptor 2 (1 entity in total) |
Functional Keywords | vegfr, receptor tyrosine kinase, homodimer, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell junction . Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted . Isoform 3: Secreted: P35968 |
Total number of polymer chains | 3 |
Total formula weight | 12483.15 |
Authors | Mineev, K.S.,Arseniev, A.A.,Shulepko, M.,Lyukmanova, E.N.,Kirpichnikov, M.P. (deposition date: 2013-10-02, release date: 2014-07-30, Last modification date: 2024-05-15) |
Primary citation | Manni, S.,Mineev, K.S.,Usmanova, D.,Lyukmanova, E.N.,Shulepko, M.A.,Kirpichnikov, M.P.,Winter, J.,Matkovic, M.,Deupi, X.,Arseniev, A.S.,Ballmer-Hofer, K. Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation Structure, 22:1077-1089, 2014 Cited by PubMed: 24980797DOI: 10.1016/j.str.2014.05.010 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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