2MDR

Solution structure of the third double-stranded RNA-binding domain (dsRBD3) of human adenosine-deaminase ADAR1

Summary for 2MDR

Entry DOI	10.2210/pdb2mdr/pdb
NMR Information	BMRB: 19502
Descriptor	Double-stranded RNA-specific adenosine deaminase (1 entity in total)
Functional Keywords	deaminase, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Isoform 1: Cytoplasm. Isoform 5: Cytoplasm: P55265
Total number of polymer chains	1
Total formula weight	12492.19
Authors	Barraud, P.,Banerjee, S.,Mohamed, W.I.,Jantsch, M.F.,Allain, F.H. (deposition date: 2013-09-17, release date: 2014-04-30, Last modification date: 2023-06-14)
Primary citation	Barraud, P.,Banerjee, S.,Mohamed, W.I.,Jantsch, M.F.,Allain, F.H. A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. Proc.Natl.Acad.Sci.USA, 111:E1852-E1861, 2014 Cited by PubMed: 24753571 DOI: 10.1073/pnas.1323698111 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation