2MDQ
A Novel 4/7-Conotoxin LvIA from Conus lividus that Selectively Blocks 3 2 vs. 6/3 2 3 Nicotinic Acetylcholine Receptors
Summary for 2MDQ
Entry DOI | 10.2210/pdb2mdq/pdb |
NMR Information | BMRB: 19501 |
Descriptor | Alpha-conotoxin-like (1 entity in total) |
Functional Keywords | conotoxin, disulfide rich, toxin, alfa-conotoxins, nicotinic acetylcholine receptor |
Biological source | Conus lividus (Livid cone) |
Cellular location | Secreted (By similarity): L8BU87 |
Total number of polymer chains | 1 |
Total formula weight | 1684.92 |
Authors | Schroeder, C.I. (deposition date: 2013-09-16, release date: 2014-02-12, Last modification date: 2023-12-27) |
Primary citation | Luo, S.,Zhangsun, D.,Schroeder, C.I.,Zhu, X.,Hu, Y.,Wu, Y.,Weltzin, M.M.,Eberhard, S.,Kaas, Q.,Craik, D.J.,McIntosh, J.M.,Whiteaker, P. A novel alpha 4/7-conotoxin LvIA from Conus lividus that selectively blocks alpha 3 beta 2 vs. alpha 6/ alpha 3 beta 2 beta 3 nicotinic acetylcholine receptors. Faseb J., 28:1842-1853, 2014 Cited by PubMed: 24398291DOI: 10.1096/fj.13-244103 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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