2M97

Optimized Ratiometric Calcium Sensors For Functional In Vivo Imaging of Neurons and T-Lymphocytes

Summary for 2M97

Entry DOI	10.2210/pdb2m97/pdb
NMR Information	BMRB: 19285
Descriptor	Optimized Ratiometric Calcium Sensor (1 entity in total)
Functional Keywords	calcium biosensors, metal binding protein
Biological source	Opsanus tau
Total number of polymer chains	1
Total formula weight	8066.65
Authors	Russo, L.,Becker, S.,Griesinger, C. (deposition date: 2013-06-04, release date: 2014-01-01, Last modification date: 2014-02-12)
Primary citation	Thestrup, T.,Litzlbauer, J.,Bartholomaus, I.,Mues, M.,Russo, L.,Dana, H.,Kovalchuk, Y.,Liang, Y.,Kalamakis, G.,Laukat, Y.,Becker, S.,Witte, G.,Geiger, A.,Allen, T.,Rome, L.C.,Chen, T.W.,Kim, D.S.,Garaschuk, O.,Griesinger, C.,Griesbeck, O. Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes. Nat.Methods, 11:175-182, 2014 Cited by PubMed: 24390440 DOI: 10.1038/nmeth.2773 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation