2LZL
FGFR3tm
Summary for 2LZL
Entry DOI | 10.2210/pdb2lzl/pdb |
NMR Information | BMRB: 18763 |
Descriptor | Fibroblast growth factor receptor 3 (1 entity in total) |
Functional Keywords | transmembrane domain, fibroblast growth factor receptor, dimerization, tyrosine kinase, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Isoform 3: Secreted. Isoform 4: Cell membrane; Single-pass type I membrane protein (By similarity): P22607 |
Total number of polymer chains | 2 |
Total formula weight | 9208.65 |
Authors | Lesovoy, D.M.,Bocharov, E.V.,Goncharuk, S.A.,Arseniev, A.S. (deposition date: 2012-10-04, release date: 2013-10-09, Last modification date: 2024-05-01) |
Primary citation | Bocharov, E.V.,Lesovoy, D.M.,Goncharuk, S.A.,Goncharuk, M.V.,Hristova, K.,Arseniev, A.S. Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies. Structure, 21:2087-2093, 2013 Cited by PubMed: 24120763DOI: 10.1016/j.str.2013.08.026 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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