2LWE
Solution structure of mutant (T170E) second CARD of human RIG-I
Summary for 2LWE
Entry DOI | 10.2210/pdb2lwe/pdb |
Related | 2LWD |
NMR Information | BMRB: 18623 |
Descriptor | Probable ATP-dependent RNA helicase DDX58 (1 entity in total) |
Functional Keywords | rig-i, card, sensor, viral rna, helicase, phosphomemetic mutant, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O95786 |
Total number of polymer chains | 1 |
Total formula weight | 11810.91 |
Authors | Dutta, K.,Ferrage, F.,Aggarwal, A. (deposition date: 2012-07-27, release date: 2012-10-31, Last modification date: 2024-05-01) |
Primary citation | Ferrage, F.,Dutta, K.,Nistal-Villan, E.,Patel, J.R.,Sanchez-Aparicio, M.T.,De Ioannes, P.,Buku, A.,Aseguinolaza, G.G.,Garcia-Sastre, A.,Aggarwal, A.K. Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation. Structure, 20:2048-2061, 2012 Cited by PubMed: 23063562DOI: 10.1016/j.str.2012.09.003 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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