2LVZ

Solution structure of a Eosinophil Cationic Protein-trisaccharide heparin mimetic complex

Summary for 2LVZ

Entry DOI	10.2210/pdb2lvz/pdb
NMR Information	BMRB: 18596
Descriptor	Eosinophil cationic protein, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-propan-2-yl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside (2 entities in total)
Functional Keywords	heparin, molecular recognition, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	16557.72
Authors	Garcia Mayoral, M.,Canales, A.,Diaz, D.,Lopez Prados, J.,Moussaoui, M.,de Paz, J.,Angulo, J.,Nieto, P.,Jimenez Barbero, J.,Boix, E.,Bruix, M. (deposition date: 2012-07-17, release date: 2013-07-31, Last modification date: 2020-07-29)
Primary citation	Garcia-Mayoral, M.F.,Canales, A.,Diaz, D.,Lopez-Prados, J.,Moussaoui, M.,de Paz, J.L.,Angulo, J.,Nieto, P.M.,Jimenez-Barbero, J.,Boix, E.,Bruix, M. Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR. Acs Chem.Biol., 8:144-151, 2013 Cited by PubMed: 23025322 DOI: 10.1021/cb300386v PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation