2LSR

Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide of cadherin23

Summary for 2LSR

• Entry DOI: 10.2210/pdb2lsr/pdb
• Related: 2KBQ 2KBR
• NMR Information: BMRB: 18441
• Descriptor: Harmonin, peptide from Cadherin-23 (2 entities in total)
• Functional Keywords: protein complex, usher syndrome, structural protein-cell adhesion complex, structural protein/cell adhesion
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 11475.39

Authors

Pan, L.,Wu, L.,Zhang, C.,Zhang, M. (deposition date: 2012-05-04, release date: 2012-08-15, Last modification date: 2023-06-14)

• Primary citation: Wu, L.,Pan, L.,Zhang, C.,Zhang, M.; Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia.; J.Biol.Chem., 287:33460-33471, 2012; PubMed: 22879593; DOI: 10.1074/jbc.M112.378505

Experimental method

SOLUTION NMR