2LMP

Structural Model for a 40-residue Beta-Amyloid Fibril with Three-Fold Symmetry, Positive Stagger

Summary for 2LMP

• Entry DOI: 10.2210/pdb2lmp/pdb
• Related: 2LMN 2LMO 2LMQ
• NMR Information: BMRB: 18129
• Descriptor: Beta-amyloid protein 40 (1 entity in total)
• Functional Keywords: alzheimer's disease, three-fold symmetry, protein fibril
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P05067
• Total number of polymer chains: 18
• Total formula weight: 78045.34

Authors

Tycko, R.,Paravastu, A. (deposition date: 2011-12-08, release date: 2011-12-28)

• Primary citation: Paravastu, A.,Leapman, R.,Yau, W.,Tycko, R.; Molecular structural basis for polymorphism in Alzheimer's beta-amyloid fibrils; Proc.Natl.Acad.Sci.USA, 105:18349-18354, 2008; PubMed: 19015532

Experimental method

SOLID-STATE NMR