2LH8

Syrian hamster prion protein with thiamine

Summary for 2LH8

• Entry DOI: 10.2210/pdb2lh8/pdb
• NMR Information: BMRB: 17834
• Descriptor: Major prion protein, 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM (2 entities in total)
• Functional Keywords: prion, thiamine, membrane protein
• Biological source: Mesocricetus auratus (Syrian golden hamster)
• Cellular location: Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04273
• Total number of polymer chains: 1
• Total formula weight: 12723.15

Authors

Perez-Pineiro, R.,Bjorndahl, T.C.,Berjanskii, M.,Hau, D.,Li, L.,Huang, A.,Lee, R.,Gibbs, E.,Ladner, C.,Wei Dong, Y.,Abera, A.,Cashman, N.R.,Wishart, D. (deposition date: 2011-08-05, release date: 2011-09-14, Last modification date: 2011-11-30)

• Primary citation: Perez-Pineiro, R.,Bjorndahl, T.C.,Berjanskii, M.V.,Hau, D.,Li, L.,Huang, A.,Lee, R.,Gibbs, E.,Ladner, C.,Dong, Y.W.,Abera, A.,Cashman, N.R.,Wishart, D.S.; The prion protein binds thiamine.; Febs J., 278:4002-4014, 2011; PubMed: 21848803; DOI: 10.1111/j.1742-4658.2011.08304.x

Experimental method

SOLUTION NMR