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2L2B

Structure of StnII-Y111N, a mutant of the sea anemone actinoporin Sticholysin II

Summary for 2L2B
Entry DOI10.2210/pdb2l2b/pdb
DescriptorSticholysin-2 (1 entity in total)
Functional Keywordsactinoporin sticholysin variant, pore forming toxin, toxin
Biological sourceStichodactyla helianthus (Carribean sea anemone)
Cellular locationSecreted: P07845
Total number of polymer chains1
Total formula weight19253.77
Authors
Pardo-Cea, M.A.,Bruix, M.,Santoro, J. (deposition date: 2010-08-16, release date: 2011-06-29, Last modification date: 2012-02-08)
Primary citationPardo-Cea, M.A.,Castrillo, I.,Alegre-Cebollada, J.,Martinez-Del-Pozo, A.,Gavilanes, J.G.,Bruix, M.
Intrinsic local disorder and a network of charge-charge interactions are key to actinoporin membrane disruption and cytotoxicity.
Febs J., 278:2080-2089, 2011
Cited by
PubMed: 21481191
DOI: 10.1111/j.1742-4658.2011.08123.x
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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