2L1R

The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I

Summary for 2L1R

• Entry DOI: 10.2210/pdb2l1r/pdb
• Related: 1dtl 1lxf 1wrk 1ytz 2kfx 2krd
• NMR Information: BMRB: 17103
• Descriptor: Troponin C, Troponin I, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: troponin c, troponin i, ca2+-sensitizer, dfbp-o, n-domain, metal binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 12594.31

Authors

Robertson, I.M.,Sun, Y.,Li, M.X.,Sykes, B.D. (deposition date: 2010-08-03, release date: 2010-08-18, Last modification date: 2011-07-13)

• Primary citation: Robertson, I.M.,Sun, Y.B.,Li, M.X.,Sykes, B.D.; A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex.; J.MOL.CELL.CARDIOL., 49:1031-1041, 2010; PubMed: 20801130; DOI: 10.1016/j.yjmcc.2010.08.019

Experimental method

SOLUTION NMR