2KVM
Solution structure of the CBX7 chromodomain in complex with a H3K27me2 peptide
Summary for 2KVM
Entry DOI | 10.2210/pdb2kvm/pdb |
NMR Information | BMRB: 16778 |
Descriptor | Chromobox protein homolog 7, histone H3 peptide (residues 15-30) with dimethylated lysine 27 (2 entities in total) |
Functional Keywords | histone modification, lysine methylation, chromobox, polycomb, chromatin-binding, chromatin regulator, nucleus, repressor, transcription, transcription regulation |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 10564.22 |
Authors | |
Primary citation | Yap, K.L.,Li, S.,Munoz-Cabello, A.M.,Raguz, S.,Zeng, L.,Mujtaba, S.,Gil, J.,Walsh, M.J.,Zhou, M.M. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol.Cell, 38:662-674, 2010 Cited by PubMed: 20541999DOI: 10.1016/j.molcel.2010.03.021 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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